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David Champagne

Senior PartnerLondon

Serves global pharmaceutical clients with their digital and analytics transformations as a member of the McKinsey Digital Practice

David leads McKinsey’s global scientific AI work, helping clients in the life sciences industry and beyond drive the next frontier of R&D productivity. This work covers a broad range of AI capabilities across biology, chemistry, materials, and physics. David brings together teams of scientific experts from McKinsey’s industry practices with deep technology expertise from QuantumBlack, AI by McKinsey to create strategies, blueprints, and roadmaps for the technology-driven transformation of product discovery and development processes in industries where science is at the core of innovation.

In pharma, where he spends most of his time, this means leveraging in silico methods—foundation models, machine learning, causal inference, knowledge graphs, and various modalities of scientific data across molecules, biological pathways, and patients—to expand the search space for discovery of new drugs, improve their properties through design and optimization, and develop the scientific parameters of clinical trials to improve their probability of success and reduce costs for sponsors and burden on patients.

In his client work, David focuses on:

  • research acceleration: redesigning early stage discovery workflows using AI-driven hypothesis generation, active learning loops, and experiment automation to shrink design-make-test-analyze (DMTA) cycles
  • development optimization: applying the latest advances in AI-powered surrogate modeling, trial simulation, and patient segmentation to de-risk pipelines, shorten timelines, and increase the probability of success
  • next-gen evidence generation: leveraging the latest techniques in causal machine learning to build at-scale evidence-generation engines powering the full range of internal strategic decisions across functions and steady streams of external scientific publications on the safety and effectiveness of drugs
  • rewiring of R&D domains: supporting clients with the full end-to-end reimagination of key domains of work, reengineering processes to embed and implement AI capabilities and their enablers across culture, operating model, data and tech architecture, governance, and talent

Before joining McKinsey, David obtained a PhD in electrical engineering from Princeton University, where his dissertation explored computer security architecture. He holds five US patents in system and processor security.

Published Work

Quarterly value releases: Transforming pharma through digital and analytics—fast,” McKinsey & Company, November 2023

Generating real-world evidence at scale using advanced analytics,” McKinsey & Company, March 2022

Creating value from next-generation real-world evidence,” McKinsey & Company, July 2020

Machine learning and therapeutics 2.0: Avoiding hype, realizing potential,” McKinsey & Company, December 2018

How pharma can win in a digital world,” McKinsey & Company, December 2015

Education

Princeton University
PhD, electrical engineering